胰岛素c肽试验

定义

c -肽 is a substance that is created when the hormone insulin is produced and released into the body. The insulin c -肽 test measures the amount of this product in the blood.

选择的名字

c -肽

如何执行测试

A 血液样本 是必要的.

How to Prepare for the Test

Preparation for the test depends on the reason for the c -肽 measurement. Ask your health care provider if you should not eat (fast) before the test. Your provider may ask you to stop taking medicines that can affect the test results.

考试的感觉如何

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. 这很快就会消失.

为什么要进行测试

c -肽 is measured to tell the difference between insulin the body produces and insulin that is injected into the body.

Someone with type 1 or type 2 diabetes may have their c -肽 level measured to see if their body is still producing insulin. c -肽 is also measured in case of low blood sugar to see if the person's body is producing too much insulin.

The test is also often ordered to check if certain medicines that can help the body produce more insulin, such as glucagon-like peptide 1 analogs (GLP-1) or DPP IV inhibitors would work in an individual patient.

正常的结果

A normal result is between 0.5 to 2.0 nanograms per milliliter (ng/mL), or 0.2 to 0.8 nanomoles per liter (nmol/L).

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

Normal c -肽 level is based on blood sugar level. c -肽 is a sign that your body is producing insulin. A low level (or no c -肽) indicates that your pancreas is producing little or no insulin.

• A low level may be normal if you have not eaten recently. Your blood sugar and insulin levels would naturally be low then.
• A low level is abnormal if your blood sugar is high and your body should be making insulin at that time.

People with type 2 diabetes, obesity, or insulin resistance may have a high c -肽 level. This means their body is producing a lot of insulin to keep (or try to keep) their blood sugar normal.

风险

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a 血液样本 from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

• 出血
• Fainting or feeling lightheaded
• Multiple punctures to try to locate veins
• Hematoma (blood buildup under the skin)
• Infection (a slight risk any time the skin is broken)

参考文献

Atkinson MA, McGill DE, Dassau E, Laffel L. 1型糖尿病. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14日艾德. Philadelphia, PA: Elsevier; 2020:chap 36.

陈国强，张国强. c -肽 (connecting peptide) - serum. In: 陈国强，张国强, eds. Laboratory Tests and Diagnostic Procedures. 6日艾德. Philadelphia, PA: Elsevier; 2013:391-392.

Kahn CR, Ferris HA, O'Neill BT. Pathophysiology of type 2 diabetes mellitus. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14日艾德. Philadelphia, PA: Elsevier; 2020:chap 34.

皮特里JR，博伊尔JG. 糖尿病. In: Penman ID, Ralston SH, Strachan MWJ, Hobson RP, eds. Davidson's Principles and Practice of Medicine. 24日艾德. Philadelphia, PA: Elsevier; 2023:chap 21.