DHEA-sulfate测试

定义

DHEA stands for dehydroepiandrosterone. It is a hormone produced by the 肾上腺 in both men and women. It can be converted to other hormones that have weak male (androgenic) effects. The DHEA-sulfate测试 measures the amount of DHEA-sulfate in the blood.

选择的名字

Serum DHEA-sulfate; Dehydroepiandrosterone-sulfate test; DHEA-sulfate - serum

如何执行测试

A 血液样本 是必要的.

如何准备考试

不需要特别准备. 然而, tell your health care provider if you are taking any vitamins or supplements that contain DHEA or DHEA-sulfate.

考试的感觉如何

When the needle is inserted to draw blood, some people feel moderate pain. 其他人只感到刺痛或刺痛. Afterward, there may be some throbbing or a slight bruise. 这很快就会消失.

为什么要进行测试

This test is done to check the function of the two 肾上腺. One of these glands sits above each kidney. They are one of the major sources of androgens in women.

Although DHEA-sulfate is the most abundant hormone in the body, its exact function is still not known.

• In men, the male hormone effect may not be important if testosterone level is normal.
• In women, DHEA contributes to normal libido and sexual satisfaction.
• DHEA may also have effects on the immune system.

The DHEA-sulfate测试 is often done in women who show signs of having excess male hormones. Some of these signs are male body changes, 毛发生长过多, 油性皮肤, 痤疮, 月经不调, 或者怀孕的问题.

It may also be done in women who are concerned about low libido or decreased sexual satisfaction who have pituitary or adrenal gland disorders.

The test is also done in children who are 成熟得太早 (性早熟).

正常的结果

Normal blood levels of DHEA-sulfate can differ by sex and age.

Typical normal ranges for females are:

• Ages 18 to 19: 145 to 395 micrograms per deciliter (µg/dL) or 3.92 to 10.66微摩尔/升(µmol/L)
• 20至29岁:65至380微克/分升或1.75 to 10.26µmol / L
• 30至39岁:45至270微克/分升或1.22 to 7.29µmol / L
• 40至49岁:32至240微克/分升或0.86 to 6.48µmol / L
• 50至59岁:26至200微克/分升或0.70 to 5.40µmol / L
• 60至69岁:13至130微克/分升或0.35 to 3.51µmol / L
• Ages 69 and older: 17 to 90 µg/dL or 0.46 to 2.43µmol / L

男性的正常范围是:

• Ages 18 to 19: 108 to 441 µg/dL or 2.92 to 11.91µmol / L
• Ages 20 to 29: 280 to 640 µg/dL or 7.56 to 17.28µmol / L
• Ages 30 to 39: 120 to 520 µg/dL or 3.24 to 14.04µmol / L
• 40至49岁:95至530微克/分升或2.56 to 14.31µmol / L
• 50至59岁:70至310微克/分升或1.89 to 8.37µmol / L
• 60至69岁:42至290微克/分升或1.13 to 7.83µmol / L
• Ages 69 and older: 28 to 175 µg/dL or 0.76 to 4.72µmol / L

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different specimens. Talk to your health care provider about the meaning of your specific test results.

异常结果意味着什么

An increase in DHEA-sulfate may be due to:

• 一种常见的遗传疾病叫做 先天性肾上腺增生.
• A tumor of the adrenal gland, which can be benign or be a cancer.
• A common problem in women younger than 50, called 多囊卵巢综合征.
• Body changes of a girl in puberty happening earlier than normal.

A decrease in DHEA sulfate may be due to:

• 肾上腺 disorders that produce lower than normal amounts of adrenal hormones, 包括肾上腺功能不全和 艾迪生疾病
• The pituitary gland not producing normal amounts of its hormones (垂体机能减退)
• 服用糖皮质激素药物

DHEA levels normally decline with age in both men and women. There is no reliable evidence that taking DHEA supplements prevents aging-related conditions.

风险

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a 血液样本 from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:

• 大出血
• 昏厥或感到头晕
• 多次穿刺定位静脉
• Hematoma (blood buildup under the skin)
• Infection (a slight risk any time the skin is broken)

参考文献

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Nakamoto J. 内分泌检测. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. 内分泌学:成人和儿童. 7日艾德. Philadelphia, PA: Elsevier Saunders; 2016:chap 154.

内伦兹RD，两位B. Reproductive endocrinology and related disorders. In: Rifai N, Chiu RWK, Young I, Burnham CAD, Wittwer CA, eds. Tietz Textbook of Laboratory Medicine. 7日艾德. St Louis, MO: Elsevier; 2023:chap 58.

Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, and 多囊卵巢综合征. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. 内分泌学:成人和儿童. 7日艾德. Philadelphia, PA: Elsevier Saunders; 2016:chap 133.

van den Beld AW, Lamberts SWJ. 内分泌学和衰老. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. 威廉斯内分泌学教科书. 14日艾德. Philadelphia, PA: Elsevier; 2020:chap 28.